Do stress-related psychosocial factors contribute to cancer incidence and survival?
August 31st, 2008
United Kingdom
Yoichi Chida , Mark Hamer, Jane Wardle, Andrew Steptoe
Examining the impact of stress-related psychosocial factors on cancer incidence, survival, and mortality
Nature Reviews Clinical Oncology
DOI: 10.1038/ncponc1134
Posted byLuciana Ramos
Pending staff verification
Notify
Abstract/Description
A substantial body of research has investigated the associations between stress-related psychosocial factors and cancer outcomes. Previous narrative reviews have been inconclusive. In this Review, we evaluated longitudinal associations between stress and cancer using meta-analytic methods. The results of 165 studies indicate that stress-related psychosocial factors are associated with higher cancer incidence in initially healthy populations (P = 0.005); in addition, poorer survival in patients with diagnosed cancer was noted in 330 studies (P