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The Impact of Studying Brain Plasticity

February 26th, 2019
Seville, Spain
Pedro Mateos-Aparicio, Antonio Rodríguez-Moreno
The article discusses brain plasticity, the nervous system’s ability to reorganize structure and function in response to experience. It reviews the history and mechanisms of synaptic plasticity and emphasizes its central role in learning, development, and recovery, while highlighting ongoing challenges in understanding how plasticity shapes the brain.
Frontiers in Cellular Neuroscience
DOI: 10.3389/fncel.2019.00066
Posted byRiley Fitzpatrick

Abstract/Description

Neural plasticity, also known as neuroplasticity or brain plasticity, can be defined as the ability of the nervous system to change its activity in response to intrinsic or extrinsic stimuli by reorganizing its structure, functions, or connections. A fundamental property of neurons is their ability to modify
the strength and efficacy of synaptic transmission through a diverse number of activity-dependent mechanisms, typically referred as synaptic plasticity. Research in the past century has showed that neural plasticity is a fundamental property of nervous systems in species from insects to
humans. Indeed, studies into synaptic plasticity have not only been an important driving force in neuroscience research but they are also contributing to the well-being of our societies as this phenomenon is involved in learning and memory, brain development and homeostasis, sensorial
training, and recovery from brain lesions. However, despite intense research into the mechanisms governing synaptic plasticity, it is still not clear exactly how plasticity shapes brain morphology and physiology. Thus, studying synaptic plasticity is clearly still important if we wish to fully understand
how the brain works.

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